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Physical properties of a porcine internal thoracic artery fixed with an epoxy compound

Paper ID Volume ID Publish Year Pages File Format Full-Text
14007 1058 1996 9 PDF Available
Title
Physical properties of a porcine internal thoracic artery fixed with an epoxy compound
Abstract

This study aimed to investigate the physical properties of a porcine internal thoracic artery fixed with an epoxy compound. Fresh and glutaraldehyde-fixed porcine arteries were used as controls. Both the epoxy-fixed and glutaraldehyde-fixed porcine arteries showed significant increases in fixation index and denaturation temperature as compared to the fresh one. Additionally, the resistance of porcine arteries against bacterial collagenase In vitro degradation increased significantly after cross-linking with the epoxy compound or glutaraldehyde. The reduction of the tensile strength of the epoxy-fixed artery after bacterial collagenase degradation was more severe than in its glutaraldehyde-fixed counterpart. Generally, with increasing pH, temperature or fixative concentration, the fixation indices and denaturation temperatures of the epoxy-fixed porcine arteries increased. The results obtained in this study may be used to optimize the fixation process for developing a small-diameter biological vascular graft fixed by an epoxy compound.

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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 17, Issue 24, 1996, Pages 2357-2365
Authors
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us