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Spark plasma sintering synthesis of porous nanocrystalline titanium alloys for biomedical applications

Paper ID Volume ID Publish Year Pages File Format Full-Text
14144 1175 2007 4 PDF Available
Title
Spark plasma sintering synthesis of porous nanocrystalline titanium alloys for biomedical applications
Abstract

The reason for the extended use of titanium and its alloys as implant biomaterials stems from their lower elastic modulus, their superior biocompatibility and improved corrosion resistance compared to the more conventional stainless steel and cobalt-based alloys [Niinomi, M., Hattori, T., Niwa, S., 2004. Material characteristics and biocompatibility of low rigidity titanium alloys for biomedical applications. In: Jaszemski, M.J., Trantolo, D.J., Lewandrowski, K.U., Hasirci, V., Altobelli, D.E., Wise, D.L. (Eds.), Biomaterials in Orthopedics. Marcel Dekker Inc., New York, pp. 41–62]. Nanostructured titanium-based biomaterials with tailored porosity are important for cell-adhesion, viability, differentiation and growth. Newer technologies like foaming or low-density core processing were recently used for the surface modification of titanium alloy implant bodies to stimulate bone in-growth and improve osseointegration and cell-adhesion, which in turn play a key role in the acceptance of the implants. We here report preliminary results concerning the synthesis of mesoporous titanium alloy bodies by spark plasma sintering. Nanocrystalline cp Ti, Ti–6Al–4V, Ti–Al–V–Cr and Ti–Mn–V–Cr–Al alloy powders were prepared by high-energy wet-milling and sintered to either full-density (cp Ti, Ti–Al–V) or uniform porous (Ti–Al–V–Cr, Ti–Mn–V–Cr–Al) bulk specimens by field-assisted spark plasma sintering (FAST/SPS). Cellular interactions with the porous titanium alloy surfaces were tested with osteoblast-like human MG-63 cells. Cell morphology was investigated by scanning electron microscopy (SEM). The SEM analysis results were correlated with the alloy chemistry and the topographic features of the surface, namely porosity and roughness.

Keywords
Porous titanium surfaces; Spark plasma sintering; Cell morphology
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Spark plasma sintering synthesis of porous nanocrystalline titanium alloys for biomedical applications
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomolecular Engineering - Volume 24, Issue 5, November 2007, Pages 564–567
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us