fulltext.study @t Gmail

Aptamer-based ‘point-of-care testing’

Paper ID Volume ID Publish Year Pages File Format Full-Text
14201 1188 2016 11 PDF Available
Title
Aptamer-based ‘point-of-care testing’
Abstract

•Aptamers are single-stranded oligonucleotides that can be artificially generated by a method called ‘SELEX’.•We discussed novel, portable, and aptamer-based sensing strategies that have been used in ‘point-of-care testing’.•Technical elements, assay formats for diseases are discussed with aptasensors.•Comparison has been set based-on conventional assay formats.•Detections of wide range of target molecules are discussed.

Aptamers are single-stranded oligonucleotides that can be artificially generated by a method called Systematic evolution of ligands by exponential enrichment (SELEX). The generated aptamers have been assessed for high-performance sensing applications due to their appealing characteristics. With either aptamers alone or complementing with antibodies, several high sensitive and portable sensors have been demonstrated for use in ‘point-of-care testing’. Due to their high suitability and flexibility, aptamers are conjugated with nanostructures and utilized in field applications. Moreover, aptamers are more amenable to chemical modifications, making them capable of utilization with most developed sensors. In this overview, we discuss novel, portable, and aptamer-based sensing strategies that are suitable for ‘point-of-care testing’.

Keywords
Aptamer; SELEX; Sensor; Antibody; Portable
First Page Preview
Aptamer-based ‘point-of-care testing’
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 34, Issue 3, May–June 2016, Pages 198–208
Authors
, , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us