fulltext.study @t Gmail

Recent advances in topical delivery of proteins and peptides mediated by soft matter nanocarriers

Paper ID Volume ID Publish Year Pages File Format Full-Text
14228 1194 2015 15 PDF Available
Title
Recent advances in topical delivery of proteins and peptides mediated by soft matter nanocarriers
Abstract

Proteins and peptides are increasingly important therapeutics for the treatment of severe and complex diseases like cancer or autoimmune diseases due to their high specificity and potency. Their unique structure and labile physicochemical properties, however, require special attention in the production and formulation process as well as during administration.Aside from conventional systemic injections, the topical application of proteins and peptides is an appealing alternative due to its non-invasive nature and thus high acceptance by patients. For this approach, soft matter nanocarriers are interesting delivery systems which offer beneficial properties such as high biocompatibility, easiness of modifications, as well as targeted drug delivery and release.This review aims to highlight and discuss technological developments in the field of soft matter nanocarriers for the delivery of proteins and peptides via the skin, the eye, the nose, and the lung, and to provide insights in advantages, limitations, and practicability of recent advances.

Keywords
Soft matter nanocarrier; Topical delivery; Biopharmaceuticals; Proteins; Peptides; Targeted drug delivery; Dermal; Ocular; Nasal; Pulmonary
First Page Preview
Recent advances in topical delivery of proteins and peptides mediated by soft matter nanocarriers
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 33, Issue 6, Part 3, 1 November 2015, Pages 1355–1369
Authors
, , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us