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Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals

Paper ID Volume ID Publish Year Pages File Format Full-Text
14233 1195 2015 8 PDF Available
Title
Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals
Abstract

Industrial bio-processes for fine chemical production are increasingly relying on cell factories developed through metabolic engineering and synthetic biology. The use of high throughput techniques and automation for the design of cell factories, and especially platform strains, has played an important role in the transition from laboratory research to industrial production. Model organisms such as Saccharomyces cerevisiae and Escherichia coli remain widely used host strains for industrial production due to their robust and desirable traits. This review describes some of the bio-based fine chemicals that have reached the market, key metabolic engineering tools that have allowed this to happen and some of the companies that are currently utilizing these technologies for developing industrial production processes.

Keywords
Synthetic biology; Metabolic engineering; Cell factories; Saccharomyces cerevisiae; Escherichia coli; Industrial production
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 33, Issue 7, 15 November 2015, Pages 1395–1402
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us