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Modularization of genetic elements promotes synthetic metabolic engineering

Paper ID Volume ID Publish Year Pages File Format Full-Text
14235 1195 2015 8 PDF Available
Title
Modularization of genetic elements promotes synthetic metabolic engineering
Abstract

In the context of emerging synthetic biology, metabolic engineering is moving to the next stage powered by new technologies. Systematical modularization of genetic elements makes it more convenient to engineer biological systems for chemical production or other desired purposes. In the past few years, progresses were made in engineering metabolic pathway using synthetic biology tools. Here, we spotlighted the topic of implementation of modularized genetic elements in metabolic engineering. First, we overviewed the principle developed for modularizing genetic elements and then discussed how the genetic modules advanced metabolic engineering studies. Next, we picked up some milestones of engineered metabolic pathway achieved in the past few years. Last, we discussed the rapid raised synthetic biology field of “building a genome” and the potential in metabolic engineering.

Keywords
Synthetic biology; Modularity engineering; Modularization; DNA assembly
First Page Preview
Modularization of genetic elements promotes synthetic metabolic engineering
Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 33, Issue 7, 15 November 2015, Pages 1412–1419
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering