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Mechanisms of acid tolerance in bacteria and prospects in biotechnology and bioremediation

Paper ID Volume ID Publish Year Pages File Format Full-Text
14241 1195 2015 9 PDF Available
Title
Mechanisms of acid tolerance in bacteria and prospects in biotechnology and bioremediation
Abstract

Acidogenic and aciduric bacteria have developed several survival systems in various acidic environments to prevent cell damage due to acid stress such as that on the human gastric surface and in the fermentation medium used for industrial production of acidic products. Common mechanisms for acid resistance in bacteria are proton pumping by F1–F0–ATPase, the glutamate decarboxylase system, formation of a protective cloud of ammonia, high cytoplasmic urease activity, repair or protection of macromolecules, and biofilm formation. The field of synthetic biology has rapidly advanced and generated an ever-increasing assortment of genetic devices and biological modules for applications in biofuel and novel biomaterial productions. Better understanding of aspects such as overproduction of general shock proteins, molecular mechanisms, and responses to cell density adopted by microorganisms for survival in low pH conditions will prove useful in synthetic biology for potential industrial and environmental applications.

Keywords
Acid resistance; F1–F0–ATPase; Glutamate decarboxylase; Macromolecule; Synthetic biology
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Mechanisms of acid tolerance in bacteria and prospects in biotechnology and bioremediation
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 33, Issue 7, 15 November 2015, Pages 1484–1492
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
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Full-text PDF Download
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