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Advances in self-assembled chitosan nanomaterials for drug delivery

Paper ID Volume ID Publish Year Pages File Format Full-Text
14250 1196 2014 16 PDF Available
Title
Advances in self-assembled chitosan nanomaterials for drug delivery
Abstract

Nanomaterials based on chitosan have emerged as promising carriers of therapeutic agents for drug delivery due to good biocompatibility, biodegradability, and low toxicity. Chitosan originated nanocarriers have been prepared by mini-emulsion, chemical or ionic gelation, coacervation/precipitation, and spray-drying methods. As alternatives to these traditional fabrication methods, self-assembled chitosan nanomaterials show significant advantages and have received growing scientific attention in recent years. Self-assembly is a spontaneous process by which organized structures with particular functions and properties could be obtained without additional complicated processing or modification steps. In this review, we focus on recent progress in the design, fabrication and physicochemical aspects of chitosan-based self-assembled nanomaterials. Their applications in drug delivery of different therapeutic agents are also discussed in details.

Keywords
Chitosan; Self-assembly; Nanomaterials; Drug delivery
First Page Preview
Advances in self-assembled chitosan nanomaterials for drug delivery
Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 32, Issue 7, 15 November 2014, Pages 1301–1316
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering