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Production of foreign proteins using plastid transformation ☆

Paper ID Volume ID Publish Year Pages File Format Full-Text
14377 1214 2012 11 PDF Available
Title
Production of foreign proteins using plastid transformation ☆
Abstract

In the past decades, the progress made in plant biotechnology has made possible the use of plants as a novel production platform for a wide range of molecules. In this context, the transformation of the plastid genome has given a huge boost to prove that plants are a promising system to produce recombinant proteins. In this review, we provide a background on plastid genetics and on the principles of this technology in higher plants. Further, we discuss the most recent biotechnological applications of plastid transformation for the production of enzymes, therapeutic proteins, antibiotics, and proteins with immunological properties. We also discuss the potential of plastid biotechnology and the novel tools developed to overcome some limitations of chloroplast transformation.

Keywords
FW, Fresh Weight; DW, Dry Weight; GlyBet, Glycine betaine; NEP, Nuclear Encoded Polymerase; PEP, Plastid Encoded Polymerase; TCP, Total Cellular Protein; TLP, Total Leaf Protein; TSP, Total Soluble Proteins; UTR, Untraslated Region; VLP, Virus-Like Partic
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Production of foreign proteins using plastid transformation ☆
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 30, Issue 2, March–April 2012, Pages 387–397
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us