fulltext.study @t Gmail

From the first to the third generation adenoviral vector: What parameters are governing the production yield?

Paper ID Volume ID Publish Year Pages File Format Full-Text
14407 1218 2009 12 PDF Available
Title
From the first to the third generation adenoviral vector: What parameters are governing the production yield?
Abstract

Human adenoviral viral vector serotype 5 (AdV) is presently the primary viral vector used in gene therapy trials. Advancements in AdV process development directly contribute to the clinical application and commercialization of the AdV gene delivery technology. Notably, the development of AdV production in suspension culture has driven the increase in AdV volumetric and specific productivity, therefore providing large quantities of AdV required for clinical studies. This review focuses on detailing the viral, cell and cell culture parameters governing the productivity of the three generations of AdV vectors.

Keywords
Adenovirus; Helper-dependent adenoviral vector; Production; Quantification
First Page Preview
From the first to the third generation adenoviral vector: What parameters are governing the production yield?
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 27, Issue 2, March–April 2009, Pages 133–144
Authors
, , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us