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Where bio meets nano: The many uses for nanoporous aluminum oxide in biotechnology

Paper ID Volume ID Publish Year Pages File Format Full-Text
14475 1223 2012 11 PDF Available
Title
Where bio meets nano: The many uses for nanoporous aluminum oxide in biotechnology
Abstract

Porous aluminum oxide (PAO) is a ceramic formed by an anodization process of pure aluminum that enables the controllable assembly of exceptionally dense and regular nanopores in a planar membrane. As a consequence, PAO has a high porosity, nanopores with high aspect ratio, biocompatibility and the potential for high sensitivity imaging and diverse surface modifications. These properties have made this unusual material attractive to a disparate set of applications. This review examines how the structure and properties of PAO connect with its present and potential uses within research and biotechnology. The role of PAO is covered in areas including microbiology, mammalian cell culture, sensitive detection methods, microarrays and other molecular assays, and in creating new nanostructures with further uses within biology.

Keywords
MALDI-MS, matrix-assisted laser desorption/ionization mass spectroscopy; PAO, porous aluminum oxide; PDMS, polydimethylsiloxane; PEG, polyethylene glycol; POP, proof of principle; SERS, surface enhanced Raman spectroscopy; SPR, surface plasmon resistanceA
First Page Preview
Where bio meets nano: The many uses for nanoporous aluminum oxide in biotechnology
Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 30, Issue 5, September–October 2012, Pages 1089–1099
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering