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Cyclosporin A — A review on fermentative production, downstream processing and pharmacological applications

Paper ID Volume ID Publish Year Pages File Format Full-Text
14553 1228 2011 18 PDF Available
Title
Cyclosporin A — A review on fermentative production, downstream processing and pharmacological applications
Abstract

In present times, the immunosuppressants have gained considerable importance in the world market. Cyclosporin A (CyA) is a cyclic undecapeptide with a variety of biological activities including immunosuppressive, anti-inflammatory, antifungal and antiparasitic properties. CyA is produced by various types of fermentation techniques using Tolypocladium inflatum. In the present review, we discuss the biosynthetic pathway, fermentative production, downstream processing and pharmacological activities of CyA.

Keywords
Cyclosporin A; Fermentation; Immunosuppressants; Tolypocladium inflatum
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Cyclosporin A — A review on fermentative production, downstream processing and pharmacological applications
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 29, Issue 4, July–August 2011, Pages 418–435
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us