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Biotechnological approaches for the production of polyhydroxyalkanoates in microorganisms and plants — A review

Paper ID Volume ID Publish Year Pages File Format Full-Text
14817 1255 2007 28 PDF Available
Title
Biotechnological approaches for the production of polyhydroxyalkanoates in microorganisms and plants — A review
Abstract

The increasing effect of non-degradable plastic wastes is a growing concern. Polyhydroxyalkanoates (PHAs), macromolecule-polyesters naturally produced by many species of microorganisms, are being considered as a replacement for conventional plastics. Unlike petroleum-derived plastics that take several decades to degrade, PHAs can be completely bio-degraded within a year by a variety of microorganisms. This biodegradation results in carbon dioxide and water, which return to the environment. Attempts based on various methods have been undertaken for mass production of PHAs. Promising strategies involve genetic engineering of microorganisms and plants to introduce production pathways. This challenge requires the expression of several genes along with optimization of PHA synthesis in the host. Although excellent progress has been made in recombinant hosts, the barriers to obtaining high quantities of PHA at low cost still remain to be solved. The commercially viable production of PHA in crops, however, appears to be a realistic goal for the future.

Keywords
ACP, acyl carrier protein; CaMV35S, cauliflower mosaic virus 35S; CoA, coenzyme A; DGAT, diacylglycerol acyltransferase; dwt, dry weight; ER, endoplasmic reticulum; fad, fatty acid desaturase; HA, 3-hydroxyalkanoate; HB, 3-hydroxybutyrate; 4HB, 4-hydroxyb
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Biotechnological approaches for the production of polyhydroxyalkanoates in microorganisms and plants — A review
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biotechnology Advances - Volume 25, Issue 2, March–April 2007, Pages 148–175
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
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Full-text PDF Download
Online Support
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