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Biological performance of hydroxyapatite–biopolymer foams: In vitro cell response

Paper ID Volume ID Publish Year Pages File Format Full-Text
1482 84 2012 9 PDF Available
Title
Biological performance of hydroxyapatite–biopolymer foams: In vitro cell response
Abstract

Uncoated and biopolymer-coated nanocrystalline hydroxyapatite (HA) macroporous foams are presented as promising candidates as scaffolds for bone tissue regeneration. To this end, foam degradability, the cytotoxic effects on osteoblast-like cells of foam degradation by-products and biocompatibility with osteoblast-like cells were assayed on the three-dimensional (3-D) foam surface. The results show that the 3-D interconnected architectural design of these HA foams allows excellent osteoblast internalization, proliferation and differentiation, exhibiting adequate colonization over the entire scaffold surface with an appropriate degradation rate without any cytotoxic effects.

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Keywords
Macroporous foam; Hydroxyapatite; In vitro cell response; Scaffolds; Biopolymer coating
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Biological performance of hydroxyapatite–biopolymer foams: In vitro cell response
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 8, Issue 2, February 2012, Pages 802–810
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us