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On the relationship between GC content and the number of predicted microRNA binding sites by MicroInspector

Paper ID Volume ID Publish Year Pages File Format Full-Text
15334 1404 2008 5 PDF Available
Title
On the relationship between GC content and the number of predicted microRNA binding sites by MicroInspector
Abstract

MicroRNA GC content and length is believed to play a role in the prediction of putative microRNA targets. MicroInspector was evaluated to determine the extent to which these characteristics of microRNAs play a role in binding site predictive accuracy. A strong bias towards under predicting the number of expected bindings sites for low GC content sequences was observed, especially for microRNAs with <50% GC content. Researchers working with organisms with unusually low GC content should be aware of this bias.

Keywords
MicroInspector; MicroRNA; Target prediction; GC content
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On the relationship between GC content and the number of predicted microRNA binding sites by MicroInspector
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Publisher
Database: Elsevier - ScienceDirect
Journal: Computational Biology and Chemistry - Volume 32, Issue 3, June 2008, Pages 222–226
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us