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Microtubule dynamics regulated by stathmin

Paper ID Volume ID Publish Year Pages File Format Full-Text
15394 1409 2008 4 PDF Available
Title
Microtubule dynamics regulated by stathmin
Abstract

Microtubules perform a variety of functions which lead to the complex regulation of intracellular transport and cell division. However, the regulation of microtubule growth is not clearly known. Based on a recent experimental finding, we explore the possibility of spatial regulation of microtubule growth by stathmin–tubulin interaction gradients. Computer simulation of the model with stathmin–tubulin interaction gradients gave regulated growth as seen in experiments. In future, the stathmin–tubulin interaction gradients can be made dynamic and its impact on the microtubule growth can be explored.

Keywords
Stathmin; Monte Carlo; Gradient region; Catastrophe; Rescue; Tubulin
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Microtubule dynamics regulated by stathmin
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Publisher
Database: Elsevier - ScienceDirect
Journal: Computational Biology and Chemistry - Volume 32, Issue 2, April 2008, Pages 141–144
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us