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Metagenomics for the discovery of novel biosurfactants of environmental interest from marine ecosystems

Paper ID Volume ID Publish Year Pages File Format Full-Text
15585 42454 2015 7 PDF Available
Title
Metagenomics for the discovery of novel biosurfactants of environmental interest from marine ecosystems
Abstract

•Partial biosurfactant genes have been heterologously expressed in S. cerevisiae.•A bacterial consortium has produced a highly active and stable biosurfactant.•The biosurfactant serrawettin has been heterologously expressed in E. coli.•Heterologous biosurfactant expression in a shotgun clone library has been achieved.

Research focused on the search for new biosurfactants aims to replace chemical surfactants, which while being cost-effective are ecologically undesirable. Metagenomics can lead to discovery of novel biosurfactants, tackling issues of low production yields. Recent successes include the heterologous production of biosurfactants. The dearth of biosurfactants discovered to date through metagenomics is puzzling given that good screening systems and heterologous host systems are available.

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Metagenomics for the discovery of novel biosurfactants of environmental interest from marine ecosystems
Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 33, June 2015, Pages 176–182
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering