fulltext.study @t Gmail

Yeast toxicogenomics: lessons from a eukaryotic cell model and cell factory

Paper ID Volume ID Publish Year Pages File Format Full-Text
15586 42454 2015 9 PDF Available
Title
Yeast toxicogenomics: lessons from a eukaryotic cell model and cell factory
Abstract

•Toxicogenomic application of S. cerevisiae as a eukaryotic model and cell factory.•Physiological genomics of the response and resistance to chemical stress in yeast.•Post-genomic approaches applied to environmental toxicology in the yeast model.

The yeast Saccharomyces cerevisiae remains a highly relevant experimental model in the field of toxicogenomics and is an important microbial cell factory for the production of added-value chemicals and biofuels. Its deep functional characterization coupled with the straightforward exploitation of Omic approaches and metabolic engineering, at the frontline of systems and synthetic biology, is instrumental to obtain mechanistic insights into the response to multiple toxicants and for the development of robust industrial strains. This critical review focuses on the current field, ranging from the identification of toxicological outcomes of exposure to environmental toxicants, with impact in risk assessment, bioremediation and plant biotechnology, to the improvement of biomass-based biorefinery processes, with applications in pharmacology and in the food and beverages industry.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (248 K)Download as PowerPoint slide

First Page Preview
Yeast toxicogenomics: lessons from a eukaryotic cell model and cell factory
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 33, June 2015, Pages 183–191
Authors
, ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us