Biomimetic conducting polymer-based tissue scaffolds
•Electrical stimulation is used in a number of FDA approved devices.•There are no FDA approved CP-based tissue scaffolds.•CP-based tissue scaffolds with biomimetic properties perform better in vitro.•CP-based biomaterials exhibit relatively low levels of immunogenicity in vivo.
Conducting polymer-based materials are promising for application as tissue scaffolds for the replacement or restoration of damaged or malfunctioning tissues, because a variety of tissues respond to electrical stimulation. This review focuses on conducting polymer-based materials with biomimetic chemical, mechanical and topological properties, and recent progress toward the fabrication of clinically relevant tissue scaffolds is highlighted.
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Journal: Current Opinion in Biotechnology - Volume 24, Issue 5, October 2013, Pages 847–854