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Tissue engineering and regenerative medicine as applied to the gastrointestinal tract

Paper ID Volume ID Publish Year Pages File Format Full-Text
15708 42470 2013 7 PDF Available
Title
Tissue engineering and regenerative medicine as applied to the gastrointestinal tract
Abstract

•Scaffolds in tissue engineering are used as temporary matrix for the cells.•In vitro and in vivo studies were conducted to test cell–biomaterial interaction.•The proposed bioengineered tissues focused on muscle and epithelial regeneration.•Scaffolds seeded with cells enhanced in vivo tissue reconstruction.

The gastrointestinal (GI) tract is a complex system characterized by multiple cell types with a determined architectural arrangement. Tissue engineering of the GI tract aims to reinstate the architecture and function of all structural layers. The key point for successful tissue regeneration includes the use of cells/biomaterials that elucidate minimal immune response after implantation. Different biomaterial choices and cell sources have been proposed to engineer the GI tract. This review summarizes the recent advances in bioengineering the GI tract with emphasis on cell sources and scaffolding biomaterials.

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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 24, Issue 5, October 2013, Pages 909–915
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us