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Engineering more than a cell: vascularization strategies in tissue engineering

Paper ID Volume ID Publish Year Pages File Format Full-Text
15914 42476 2010 6 PDF Available
Title
Engineering more than a cell: vascularization strategies in tissue engineering
Abstract

Host integration and performance of engineered tissues have been severely limited by the lack of robust strategies to generate patent vascularization and tissue perfusion. This review highlights a selection of exciting developments in vascularization approaches for tissue engineering research. Current strategies for vascularization in tissue engineering are related to growth factor signaling and delivery, cell transplantation, bioactive smart matrix materials, and directed fabrication. Application of these techniques to in vivo models has resulted in a number of robust host vascular responses, especially with synergistic and engineered bioactive systems. The future outlook of the field includes refinement and development of new technologies for vascularization and combining these techniques with functional repair models for metabolically active tissues and relevant disease states.

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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 21, Issue 5, October 2010, Pages 704–709
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us