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Organ printing: from bioprinter to organ biofabrication line

Paper ID Volume ID Publish Year Pages File Format Full-Text
15962 42479 2011 7 PDF Available
Title
Organ printing: from bioprinter to organ biofabrication line
Abstract

Organ printing, or the layer by layer additive robotic biofabrication of functional three-dimensional tissue and organ constructs using self-assembling tissue spheroid building blocks, is a rapidly emerging technology that promises to transform tissue engineering into a commercially successful biomedical industry. It is increasingly obvious that similar well-established industries implement automated robotic systems on the path to commercial translation and economic success. The use of robotic bioprinters alone however is not sufficient for the development of large industrial scale organ biofabrication. The design and development of a fully integrated organ biofabrication line is imperative for the commercial translation of organ printing technology. This paper presents recent progress and challenges in the development of the essential components of an organ biofabrication line.

► Organ printing is rapidly emerging transforming robotic biofabrication technology in tissue engineering. ► It is becoming obvious that only one robotic bioprinter is not enough to bioprint complex human organs. ► Organ biofabrication line must include cell sorter, cell differentiator, robotic tissue spheroids biofabricator, robotic bioprinter and bioreactor. ► Development of fully integrated organ biofabrication line is essential for successful commercialization of organ printing technology. ► Presented organ biofabrication line is a laboratory prototype of future human organ biofabrication plant.

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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 22, Issue 5, October 2011, Pages 667–673
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us