fulltext.study @t Gmail

Tweaking biological switches through a better understanding of bistability behavior

Paper ID Volume ID Publish Year Pages File Format Full-Text
15985 42480 2008 7 PDF Available
Title
Tweaking biological switches through a better understanding of bistability behavior
Abstract

Many biological events are binary. The switch between mutually exclusive OFF to ON state in response to a stimulus is frequently mediated by a control circuit with a positive and/or a negative feedback. Such a system typically exhibits hysteresis with its switching ON and OFF stimulus levels dependent on the current state of the system. The system can be shown to be bistable both experimentally and mathematically. Work to synthesize such switches by combining natural or engineered components has begun to illustrate the potential of such control circuits in many areas of applications.

First Page Preview
Tweaking biological switches through a better understanding of bistability behavior
Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 19, Issue 5, October 2008, Pages 475–481
Authors
, , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering