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Cranberry components for the therapy of infectious disease

Paper ID Volume ID Publish Year Pages File Format Full-Text
16024 42482 2012 5 PDF Available
Title
Cranberry components for the therapy of infectious disease
Abstract

Summary of the in vitro data support a beneficial effect of cranberry or its proanthocyanin constituents by blocking adhesion to and biofilm formation on target tissues of pathogens. In vivo data partially support these beneficial effects. Consumption of various cranberry products benefited young and elderly females in preventing urinary tract infections, and in conjunction with antibiotic treatment in eradicating Helicobacter pylori infections in women. Mouthwash supplemented with an isolated cranberry derivative reduced significantly the caryogenic mutans streptococci. None of the mice infected intranasal with lethal dose of influenza virus and treated with cranberry fraction died after two weeks. Further studies should focus on the active cranberry component as supplement for food and other products especially where whole juice or powder cannot be used.

► Anti-adhesion agents attenuate the selection of resistant bacterial strains. ► So far, cranberry is the only nutritional therapy effective in preventing infectious disease. ► Beneficiary effects of cranberries on urinary tract infections caused by E. coli was proven. ► Gastrointestinal and oral health may be better controlled by cranberry constituents. ► Cranberry constituents may play a role in preventing viral infections.

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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 23, Issue 2, April 2012, Pages 148–152
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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