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Functional foods and strategies contrasting bacterial adhesion

Paper ID Volume ID Publish Year Pages File Format Full-Text
16026 42482 2012 8 PDF Available
Title
Functional foods and strategies contrasting bacterial adhesion
Abstract

Antibacterial strategies targeting bacterial adhesion to substrates are considered a valuable alternative to traditional antibiotic therapy, in view of the great advantage they bring in combating the infectious process at the very early stage without selecting for drug resistant cells. Amongst bioactive compounds with activity against bacterial adhesion, several are found in natural food and beverages, such as cranberry, tea, coffee, wine and milk. For the analysis of their anti-infective potential, successful experimental models can be conducted using different substrates from the oral cavity. Studies conducted so far in this field allowed the discovery of a variety of anti-adhesive fractions and compounds proven to be effective against bacterial traits involved in the development of oral pathologies such as caries and gingivitis/periodontitis. Discovering new anti-adhesive compounds from natural products, unravelling and testing their prophylactic and therapeutic values, and improving their use in the general population are promising new frontiers in the global fight against human infectious diseases.

► Bacterial genetically determined and non-inherited antibiotic resistance represent a serious public health concern also having economic and social implications. ► Anti-adhesive strategies are valuable alternatives to antimicrobial therapy. ► Natural food and beverages are a source of biologically active anti-adhesive compounds. ► Successful experimental models are conducted using substrates from the oral cavity. ► Natural compounds that work against oral pathogens open the way to new perspectives in the prevention and treatment of infectious diseases.

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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 23, Issue 2, April 2012, Pages 160–167
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us