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The value of Arabidopsis research in understanding human disease states

Paper ID Volume ID Publish Year Pages File Format Full-Text
16071 42483 2011 8 PDF Available
Title
The value of Arabidopsis research in understanding human disease states
Abstract

Although Arabidopsis thaliana is traditionally viewed as the key model organism for plant biology it is becoming increasingly clear that Arabidopsis represents an invaluable tool in our efforts to understand molecular mechanisms that underpin human disease states. A comparison of the annotated Arabidopsis thaliana and human genome sequences reveals that a high percentage of genes implicated in human diseases are also present in Arabidopsis. Although Arabidopsis and humans diverged 1.6 billion years ago recent studies have demonstrated remarkable conservation of protein function and cellular processes between these seemingly distant species. In particular, cellular processes associated with neurodegenerative disorders, such as Alzheimer's and Parkinson's disease, and the neurological disorder Friedreich Ataxia have been dissected using Arabidopsis.

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The value of Arabidopsis research in understanding human disease states
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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 22, Issue 2, April 2011, Pages 300–307
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us