fulltext.study @t Gmail

Road to precision: recombinase-based targeting technologies for genome engineering

Paper ID Volume ID Publish Year Pages File Format Full-Text
16079 42484 2007 9 PDF Available
Title
Road to precision: recombinase-based targeting technologies for genome engineering
Abstract

In the past years, recombinase-based approaches for integrating transgenes into defined chromosomal loci of mammalian cells have gained increasing attention. This method is attractive since it enables to precisely integrate transgenes of interest into pre-defined integration sites, thereby allowing to predict the expression properties of a genetically manipulated cell. This review focuses on the current state of targeting strategies including RMCE employing site-specific recombinases such as Cre, Flp and ΦC31. In particular, applications for protein expression, virus production, transgenic animals and chromosome engineering are described.

First Page Preview
Road to precision: recombinase-based targeting technologies for genome engineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 18, Issue 5, October 2007, Pages 411–419
Authors
, , , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us