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Polymers to direct cell fate by controlling the microenvironment

Paper ID Volume ID Publish Year Pages File Format Full-Text
16085 42484 2007 6 PDF Available
Title
Polymers to direct cell fate by controlling the microenvironment
Abstract

Enhanced understanding of the signals within the microenvironment that regulate cell fate has led to the development of increasingly sophisticated polymeric biomaterials for tissue engineering and regenerative medicine applications. This advancement is exemplified by biomaterials with precisely controlled scaffold architecture that regulate the spatio-temporal release of growth factors and morphogens, and respond dynamically to microenvironmental cues. Further understanding of the biology, qualitatively and quantitatively, of cells within their microenvironments and at the tissue–material interface will expand the design space of future biomaterials.

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Polymers to direct cell fate by controlling the microenvironment
Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 18, Issue 5, October 2007, Pages 448–453
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering