fulltext.study @t Gmail

Systems and synthetic metabolic engineering for amino acid production – the heartbeat of industrial strain development

Paper ID Volume ID Publish Year Pages File Format Full-Text
16102 42485 2012 9 PDF Available
Title
Systems and synthetic metabolic engineering for amino acid production – the heartbeat of industrial strain development
Abstract

With a world market of more than four million tons per year, l-amino acids are among the most important products in industrial biotechnology. The recent years have seen a tremendous progress in the development of tailor-made strains for such products, intensively driven from systems metabolic engineering, which upgrades strain engineering into a concept of optimization on a global scale. This concept seems especially valuable for efficient amino acid production, demanding for a global modification of pathway fluxes – a challenge with regard to the high complexity of the underlying metabolism, superimposed by various layers of metabolic and transcriptional control.

► Systems metabolic engineering upgrades strain engineering into a global scale concept. ► Metabolic engineers have to tackle complex metabolic and regulatory networks. ► Synthetic cell factories reach the benchmarks set by classical production strains. ► Artificial pathways give access to non-natural compounds. ► Systems metabolic engineering is increasing the heartbeat of industrial strain development.

First Page Preview
Systems and synthetic metabolic engineering for amino acid production – the heartbeat of industrial strain development
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 23, Issue 5, October 2012, Pages 718–726
Authors
, ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us