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Synthetic signaling networks for therapeutic applications

Paper ID Volume ID Publish Year Pages File Format Full-Text
16109 42485 2012 7 PDF Available
Title
Synthetic signaling networks for therapeutic applications
Abstract

Synthetic signaling networks contain exogenous, modified, or rationally designed components involved in sending, receiving, and processing information from the environment and other cells. Advances in the input, output, and processing elements for such networks hold promise towards developing new therapies and prophylactics for disease. Therapeutic synthetic signaling systems are still in their infancy, but are progressing into mouse models of disease and even into clinical trials. As signaling technology matures, we will see an increase in implanted and ingested cellular therapies capable of autonomously diagnosing and treating disease. These technologies have the potential to reduce some of the burden on both patients and clinicians, contributing to more efficient and eventually personalized medicine.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (147 K)Download as PowerPoint slideHighlights► Definition of synthetic signaling. ► Advances in chemical, electrical, mechanical, photonic, and thermal signaling. ► Advanced signal processing examples. ► Applications of synthetic signaling in therapeutics and potential for future clinical use.

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Synthetic signaling networks for therapeutic applications
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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 23, Issue 5, October 2012, Pages 773–779
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us