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Engineering microbial systems to explore ecological and evolutionary dynamics

Paper ID Volume ID Publish Year Pages File Format Full-Text
16112 42485 2012 7 PDF Available
Title
Engineering microbial systems to explore ecological and evolutionary dynamics
Abstract

A major goal of biological research is to provide a mechanistic understanding of diverse biological processes. To this end, synthetic biology offers a powerful approach, whereby biological questions can be addressed in a well-defined framework. By constructing simple gene circuits, such studies have generated new insights into the design principles of gene regulatory networks. Recently, this strategy has been applied to analyze ecological and evolutionary questions, where population-level interactions are critical. Here, we highlight recent development of such systems and discuss how they were used to address problems in ecology and evolutionary biology. As illustrated by these examples, synthetic ecosystems provide a unique platform to study ecological and evolutionary phenomena that are challenging to study in their natural contexts.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (307 K)Download as PowerPoint slideHighlights► Synthetic biology offers a unique approach to addressing biological questions. ► Synthetic systems are well defined and highly controllable. ► Synthetic ecosystems have been created to study questions in ecology and evolution.

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Engineering microbial systems to explore ecological and evolutionary dynamics
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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 23, Issue 5, October 2012, Pages 791–797
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us