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Single cell metabolomics

Paper ID Volume ID Publish Year Pages File Format Full-Text
16165 42488 2011 6 PDF Available
Single cell metabolomics

Recent discoveries suggest that cells of a clonal population often display multiple metabolic phenotypes at the same time. Motivated by the success of mass spectrometry (MS) in the investigation of population-level metabolomics, the analytical community has initiated efforts towards MS-based single cell metabolomics to investigate metabolic phenomena that are buried under the population average. Here, we review the current approaches and illustrate their advantages and disadvantages. Because of significant advances in the field, different technologies are now at the verge of generating data that are useful for exploring and investigating metabolic heterogeneity.

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Single cell metabolomics
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 22, Issue 1, February 2011, Pages 26–31
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Physical Sciences and Engineering Chemical Engineering Bioengineering