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Ligand-dependent regulatory RNA parts for Synthetic Biology in eukaryotes

Paper ID Volume ID Publish Year Pages File Format Full-Text
16241 42493 2010 6 PDF Available
Title
Ligand-dependent regulatory RNA parts for Synthetic Biology in eukaryotes
Abstract

Artificial regulatory RNAs have been attracting more and more interest over the past years. Their small size, combined with versatile applications, make them promising tools for designing complex eukaryotic gene networks. A variety of such regulatory RNA parts have been developed that are capable of efficiently controlling gene expression. A common basis for many of these genetic switches is the specific ligand binding to a RNA domain, followed by a conformational change. Depending on the surroundings, this can affect transcription, translation or even RNA interference (RNAi) efficacy. This article provides a concise summary of the main controllable RNA parts thus far developed for eukaryotic systems.

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Ligand-dependent regulatory RNA parts for Synthetic Biology in eukaryotes
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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 21, Issue 6, December 2010, Pages 760–765
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us