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Location, allocation, relocation: isolating adult tissue stem cells in three dimensions

Paper ID Volume ID Publish Year Pages File Format Full-Text
16266 42495 2006 7 PDF Available
Title
Location, allocation, relocation: isolating adult tissue stem cells in three dimensions
Abstract

The literature on isolation of adult tissue stem cells is vast and disparate. To better organize the field, we redefine ‘isolation’, re-expressing it as the sum of three component vectors: location, allocation and relocation. Location is the isolation of stem cells in situ by anatomical features. Allocation is physical isolation by cell sorting. Relocation is isolation of the functional properties of a stem cell to regenerate its normal progeny when relocated to a new environment. Techniques for the allocation and relocation of stem cells from certain tissues (e.g. hematopoietic) are currently better defined than their location, whereas those of other tissues (e.g. mammary glands) have had recent advances along all three vectors. Yet another group (e.g. gastric glands), have stem cells with well characterized location, emerging techniques for allocation but still rudimentary techniques for relocation.

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Location, allocation, relocation: isolating adult tissue stem cells in three dimensions
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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 17, Issue 5, October 2006, Pages 511–517
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us