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Reproducible and reliable microarray results through quality control: good laboratory proficiency and appropriate data analysis practices are essential ☆

Paper ID Volume ID Publish Year Pages File Format Full-Text
16277 42496 2008 9 PDF Available
Title
Reproducible and reliable microarray results through quality control: good laboratory proficiency and appropriate data analysis practices are essential ☆
Abstract

Over a few short years, microarray gene expression profiling has permeated most areas of biomedical research. Microarrays are now poised to enter the more demanding realm of clinical applications. The prospect of using microarray data to derive biomarkers of disease or toxicity, predict prognosis, or select treatments raises the validity and reliability bar substantially higher. The potential future payoffs are huge in terms of faster approval of more efficacious and safer medical interventions, and a more personalized implementation of them. Arriving at the future sooner rather than later is the motivation for the FDA-led MicroArray Quality Control (MAQC) project. The widespread collaboration aims to assess achievable technical performance of microarrays and capabilities and limitations of methods for microarray data analysis.

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Reproducible and reliable microarray results through quality control: good laboratory proficiency and appropriate data analysis practices are essential ☆
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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 19, Issue 1, February 2008, Pages 10–18
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us