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Biochemical network-based drug-target prediction

Paper ID Volume ID Publish Year Pages File Format Full-Text
16299 42497 2010 6 PDF Available
Title
Biochemical network-based drug-target prediction
Abstract

The use of networks to aid the drug discovery process is a rather new but booming endeavor. A vast variety of different types of networks are being constructed and analyzed for various different tasks in drug discovery. The analysis may be at the level of establishing connectivity, topology, and graphs, or may go to a more quantitative level. We discuss here how computational systems biology approaches can aid the quantitative analysis of biochemical networks for drug-target prediction. We focus on networks and pathways in which the components are related by physical interactions or biochemical processes. We particularly discuss the potential of mathematical modeling to aid the analysis of proteins for druggability.

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Biochemical network-based drug-target prediction
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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 21, Issue 4, August 2010, Pages 511–516
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us