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Characterization and dissolution of functionalized amorphous calcium phosphate biolayers using single-splat technology

Paper ID Volume ID Publish Year Pages File Format Full-Text
1630 87 2011 6 PDF Available
Title
Characterization and dissolution of functionalized amorphous calcium phosphate biolayers using single-splat technology
Abstract

New processing routes and characterization techniques underpin further growth of biomaterials for improved performance and multifunctionality. This study investigates the characteristics and solubility of amorphous calcium phosphate (ACP) printed splats. Splats made from 20 to 60 μm molten hydroxyapatite particles were classified for shape (rounded/splashed) and cracking. Recoil of the spread droplet created a bowl-shaped splat. This has previously not been observed and could be related to the longer solidification time associated with solidification to an ACP. A central depression was created from 20 μm particles, but a bowl-shaped splat from 60 μm particles. Cracking was more prevalent for splats that solidified with an edge discontinuity. Splats immersed in pH 7.3 tris buffer displayed dissolution followed by cracking. Cracking continued over a period of 15 min as dissolution induced more cracks. Further degradation occurred by delamination of splat segments. Delamination accelerated the process of splat removal. Applied to thermal spray coatings, this highlights topography and dissolution at the splat level. The use of separate splats can potentially be used as a biolayer where splats are separate, in a line or on top of each other.

Keywords
Amorphous calcium phosphate; Splat; Solubility; Printing; Microfabrication
First Page Preview
Characterization and dissolution of functionalized amorphous calcium phosphate biolayers using single-splat technology
Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 7, Issue 5, May 2011, Pages 2270–2275
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering