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The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts

Paper ID Volume ID Publish Year Pages File Format Full-Text
1644 88 2010 6 PDF Available
Title
The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts
Abstract

A new deposition method is presented, based on electrospraying, that can build bioceramic structures with desirable surface properties. This technology allows nanoapatite crystals, including hydroxyapatite (nHA), carbonate-substituted HA (nCHA) and silicon-substituted HA (nSiHA), to be electrosprayed on glass substrates. Human osteoblast cells cultured on nSiHA showed enhanced cell attachment, proliferation and protein expression, namely alkaline phosphatase, type 1 collagen and osteocalcin, as compared to nHA and nCHA. The modification of nanoapatite by the addition of silicon into the HA lattice structure renders the electrosprayed surface more hydrophilic and electronegatively charged.

Keywords
Carbonate; Electrospraying; Nanoapatites; Osteoblasts; Silicon
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The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 6, Issue 3, March 2010, Pages 750–755
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
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