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Transcription factors for predictive plant metabolic engineering: are we there yet?

Paper ID Volume ID Publish Year Pages File Format Full-Text
16474 42504 2008 7 PDF Available
Title
Transcription factors for predictive plant metabolic engineering: are we there yet?
Abstract

Transcription factors (TFs) are considered viable alternatives to ‘single enzyme’ approaches for the manipulation of plant metabolic pathways. Because of the ability to control multiple, if not all steps in a particular metabolic pathway, TFs provide attractive tools for overcoming flux bottlenecks involving multiple enzymatic steps, or for deploying pathway genes in specific organs, cell types or even plants where they normally do not express. The potential of a TF for the predictive manipulation of plant metabolism is intimately linked to understanding how it fits in the gene regulatory organization. The knowledge gained over the past decade on how plant pathways are controlled together with increasing efforts aimed at deciphering the overall architecture of plant gene regulatory networks are starting to realize the potential of TFs for predictive plant metabolic engineering.

Keywords
bHLH, basic helix–loop–helix; bp, base pair; MYB, MYB-domain protein; RNAi, RNA interference; TAD, transcriptional activation domain; TFs, transcription factors; TT, transparent testa
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Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 19, Issue 2, April 2008, Pages 138–144
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us