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Beyond host–pathogen interactions: microbial defense strategy in the host environment

Paper ID Volume ID Publish Year Pages File Format Full-Text
16520 42506 2007 8 PDF Available
Title
Beyond host–pathogen interactions: microbial defense strategy in the host environment
Abstract

Many extracellular pathogenic bacteria colonize human or animal bodies through evasion of the host immune system, a process called host–pathogen interaction. What happens when other intruders try to invade the same host and try to establish themselves in the same niche is largely unknown. In one well-studied case, Pseudomonas aeruginosa is known to secrete the protein azurin as a weapon against such invaders as cancers, parasites and viruses. The production of such weapons by pathogenic bacteria could provide important insights into how a pathogen responds in the post-colonization state to impede other intruders for its own survival. Moreover, these molecules might find use in the pharmaceutical industry as next-generation therapeutics.

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Beyond host–pathogen interactions: microbial defense strategy in the host environment
Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 18, Issue 3, June 2007, Pages 279–286
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering