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Hydroxyapatite whisker-reinforced polyetherketoneketone bone ingrowth scaffolds

Paper ID Volume ID Publish Year Pages File Format Full-Text
1656 88 2010 8 PDF Available
Title
Hydroxyapatite whisker-reinforced polyetherketoneketone bone ingrowth scaffolds
Abstract

Hydroxyapatite (HA) whisker-reinforced polyetherketoneketone (PEKK) bone ingrowth scaffolds were prepared and characterized. High levels of porosity (75–90%) and HA whisker reinforcement (0–40 vol.%) were attained using a powder processing approach to mix the HA whiskers, PEKK powder and a NaCl porogen, followed by compression molding at 350–375 °C and particle leaching to remove the porogen. The scaffold architecture and microstructure exhibited characteristics known to be favorable for osteointegration. Scaffold porosity was interconnected with a mean pore size in the range 200–300 μm as measured by micro-computed tomography. HA whiskers were embedded within and exposed on the surface of scaffold struts, producing a microscale surface topography, shown by von Kossa staining and scanning electron microscopy. Therefore, HA whisker-reinforced PEKK bone ingrowth scaffolds may be advantageous for orthopedic implant fixation, including interbody spinal fusion.

Keywords
Bone ingrowth scaffolds; Composite; Hydroxyapatite; Micro-computed tomography; Polyetheretherketone
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Hydroxyapatite whisker-reinforced polyetherketoneketone bone ingrowth scaffolds
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 6, Issue 3, March 2010, Pages 856–863
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us