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Zinc-containing apatite layers on external fixation rods promoting cell activity

Paper ID Volume ID Publish Year Pages File Format Full-Text
1668 88 2010 7 PDF Available
Title
Zinc-containing apatite layers on external fixation rods promoting cell activity
Abstract

Zinc-containing apatite layers were successfully formed on commercially available anodically oxidized Ti external fixation rods using ZnCl2-containing supersaturated calcium phosphate solutions. With an increase in concentration of ZnCl2 in the supersaturated calcium phosphate solutions, the amounts of zinc that precipitated on the Ti external fixation rods increased (from 0 to 0.195 ± 0.020 μg cm−2); meanwhile, the amounts of calcium and phosphorus that precipitated on the Ti external fixation rods decreased (from 11.2 ± 1.5 and 4.8 ± 0.5 μg cm−2 to 2.9 ± 1.6 and 1.3 ± 0.9 μg cm−2, respectively). The zinc-containing apatite layers precipitated on the Ti external fixation rods caused a significant increase in fibroblastic proliferation, osteoblastic proliferation and differentiation in vitro. The Ti external fixation rods coated with zinc-containing apatite layers are expected to be more effective in accelerating the tissue regeneration around the surgical site than those coated with an apatite layer.

Keywords
External fixation; Zinc; Fibroblast; Osteoblast; Tissue regeneration
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 6, Issue 3, March 2010, Pages 962–968
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us