fulltext.study @t Gmail

Mapping protein–protein interactions by mass spectrometry

Paper ID Volume ID Publish Year Pages File Format Full-Text
16730 42535 2006 6 PDF Available
Title
Mapping protein–protein interactions by mass spectrometry
Abstract

Mass spectrometry is currently at the forefront of technologies for mapping protein–protein interactions, as it is a highly sensitive technique that enables the rapid identification of proteins from a variety of biological samples. When used in combination with affinity purification and/or chemical cross-linking, whole or targeted protein interaction networks can be elucidated. Several methods have recently been introduced that display increased specificity and a reduced occurrence of false-positives. In the future, information gained from human protein interaction studies could lead to the discovery of novel pathway associations and therapeutic targets.

First Page Preview
Mapping protein–protein interactions by mass spectrometry
Publisher
Database: Elsevier - ScienceDirect
Journal: Current Opinion in Biotechnology - Volume 17, Issue 4, August 2006, Pages 394–399
Authors
, ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering