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Development of a transparent, non-cytotoxic, silver ion-exchanged glass with antimicrobial activity and low ion elution

Paper ID Volume ID Publish Year Pages File Format Full-Text
16886 42620 2015 7 PDF Available
Title
Development of a transparent, non-cytotoxic, silver ion-exchanged glass with antimicrobial activity and low ion elution
Abstract

•Glass was ion-exchanged via the spreading method using AgNO3 powder.•Ag ions penetrated into the glass to the depth of 4.8 μm at 260 °C for 10 min.•Antimicrobial activity of Ag ion-exchanged glass was over 99.9% after 24 weeks.•Ag ion exchanged glass was also identified to be non-cytotoxic.•Eluted concentration of Ag ion was satisfied with the WHO standard level.

We investigated the antimicrobial, cytotoxicity, skin irritation, and ion elution behaviors of glass doped with silver ions with respect to its application to electronic equipment such as phones and tablet screens. The microbes tested were Escherichia coli, Staphylococcus aureus, and Penicillium funiculosum. AgNO3 powder was spread on both sides of aluminosilicate glass, and it was heated to 250–280 °C for 10 min. Under optimized heating conditions (260 °C, 10 min), the antimicrobial activity of ion-exchanged glass against bacteria and fungi was over 99.9% after 24 weeks. The glass failed to irritate the skin of experimental animals and was considered non-cytotoxic. The maximum amount of Ag ions that were eluted from the ion-exchanged glass into drinking water was measured at 0.037 ± 0.003 μg L−1, an amount which is several orders of magnitude below the standard limit of 0.1 mg L−1 in drinking water. Ag ion-exchanged glass had characteristics suitable for use as a display screen, such as a light transmittance of 90% and a surface roughness of 0.704 nm. Our findings suggest that glass doped with silver ions is more hygienic than non-doped glass is, and should be applied to display screens and glassware.

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Keywords
Silver ion; Ion exchange; Antimicrobial activity; Cytotoxicity; Elution behavior
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Development of a transparent, non-cytotoxic, silver ion-exchanged glass with antimicrobial activity and low ion elution
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Publisher
Database: Elsevier - ScienceDirect
Journal: Enzyme and Microbial Technology - Volume 72, May 2015, Pages 65–71
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us