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Performance of vertebral cancellous bone augmented with compliant PMMA under dynamic loads

Paper ID Volume ID Publish Year Pages File Format Full-Text
1741 90 2008 6 PDF Available
Title
Performance of vertebral cancellous bone augmented with compliant PMMA under dynamic loads
Abstract

Increased fracture risk has been reported for the adjacent vertebral bodies after vertebroplasty. This increase has been partly attributed to the high Young’s modulus of commonly used polymethylmethacrylate (PMMA). Therefore, a compliant bone cement of PMMA with a bulk modulus closer to the apparent modulus of cancellous bone has been produced. This compliant bone cement was achieved by introducing pores in the cement. Due to the reduced failure strength of that porous PMMA cement, cancellous bone augmented with such cement could deteriorate under dynamic loading. The aim of the present study was to assess the potential of acute failure, particle generation and mechanical properties of cancellous bone augmented with this compliant cement in comparison to regular cement. For this purpose, vertebral biopsies were augmented with porous- and regular PMMA bone cement, submitted to dynamic tests and compression to failure. Changes in Young’s modulus and height due to dynamic loading were determined. Afterwards, yield strength and Young’s modulus were determined by compressive tests to failure and compared to the individual composite materials. No failure occurred and no particle generation could be observed during dynamical testing for both groups. Height loss was significantly higher for the porous cement composite (0.53 ± 0.21%) in comparison to the biopsies augmented with regular cement (0.16 ± 0.1%). Young’s modulus of biopsies augmented with porous PMMA was comparable to cancellous bone or porous cement alone (200–700 MPa). The yield strength of those biopsies (21.1 ± 4.1 MPa) was around two times higher than for porous cement alone (11.6 ± 3.3 MPa).

Keywords
Vertebroplasty; Porous PMMA; Low modulus; Dynamic loading; Acute failure
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Performance of vertebral cancellous bone augmented with compliant PMMA under dynamic loads
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 4, Issue 6, November 2008, Pages 1688–1693
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us