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Modelling growth kinetics of Streptomyces coelicolor A3(2) in a pressurised membrane gradostat reactor (MGR)

Paper ID Volume ID Publish Year Pages File Format Full-Text
17421 42667 2009 8 PDF Available
Title
Modelling growth kinetics of Streptomyces coelicolor A3(2) in a pressurised membrane gradostat reactor (MGR)
Abstract

Limited information is available with regards to the microbial growth kinetics of Streptomyces coelicolor A3(2) immobilised in pressurised membrane gradostat reactors (MGR). The purpose of this study was to quantify the growth kinetics of the filamentous bacterium immobilised on the external surface of ceramic membranes. The single fibre MGR's (SFMGR) were operated using a pneumatic system to supply humidified pressurised air to the extra capillary space (ECS). The nutrient growth medium was supplied to the lumen of the ceramic membrane in the dead-end mode. The growth curve that was obtained for S. coelicolor A3(2) showed the presence of two growth cycles (biphasic growth) from ±66 to 162 h and ±162 to 354 h, respectively, with no noticeable intermediate lag phase. A faster specific growth rate of 0.049 h−1 was obtained for the first growth cycle, with a lower specific growth rate in the range of ±0.013 to 0.019 h−1 obtained for the second growth cycle. The growth kinetics of S. coelicolor A3(2) within a pressurised MGR has not been reported previously.

Keywords
ECS, extra capillary space; ISP2, International Streptomyces Project, medium 2; MBR, membrane bioreactor (MBR); MGR, membrane gradostat reactor; PID, proportional-integral-derivative; ODE, Ordinary Differential Equations Solver; S. coelicolor A3(2), Strep
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Modelling growth kinetics of Streptomyces coelicolor A3(2) in a pressurised membrane gradostat reactor (MGR)
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Publisher
Database: Elsevier - ScienceDirect
Journal: Enzyme and Microbial Technology - Volume 45, Issues 6–7, December 2009, Pages 449–456
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us