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Micropatterned TiO2 nanotube surfaces for site-selective nucleation of hydroxyapatite from simulated body fluid

Paper ID Volume ID Publish Year Pages File Format Full-Text
1826 91 2011 8 PDF Available
Title
Micropatterned TiO2 nanotube surfaces for site-selective nucleation of hydroxyapatite from simulated body fluid
Abstract

TiO2 nanotube layers can provide greatly enhanced kinetics for hydroxyapatite formation from simulated body fluid compared with smooth, compact TiO2 surfaces. In the present work we show how this contrast in reactivity can be used to create highly defined lateral microstructures where bone-like hydroxyapatite can be deposited with very high selectivity. For this we used a photolithographic approach to produce micropatterned TiO2 nanotube layers surrounded by compact oxide that were then immersed in a simulated body fluid (SBF) solution. Not only the tubular vs. flat geometry but also the finding that compact oxides created in phosphate electrolytes in particular suppress apatite deposition are crucial for a very high reactivity contrast. Overall the results show the feasibility of stimulating hydroxyapatite deposition at surface locations where needed or desired. This provides a valuable tool for biomedical device design.

Keywords
TiO2 nanotubes; Electrochemical anodization; Hydroxyapatite; Micropattern; Photolithography
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Micropatterned TiO2 nanotube surfaces for site-selective nucleation of hydroxyapatite from simulated body fluid
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 7, Issue 1, January 2011, Pages 424–431
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us