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On the design and simulation of an airlift loop bioreactor with microbubble generation by fluidic oscillation

Paper ID Volume ID Publish Year Pages File Format Full-Text
19481 43069 2009 13 PDF Available
Title
On the design and simulation of an airlift loop bioreactor with microbubble generation by fluidic oscillation
Abstract

Microbubble generation by a novel fluidic oscillator driven approach is analyzed, with a view to identifying the key design elements and their differences from standard approaches to airlift loop bioreactor design. The microbubble generation mechanism has been shown to achieve high mass transfer rates by the decrease of the bubble diameter, by hydrodynamic stabilization that avoids coalescence increasing the bubble diameter, and by longer residence times offsetting slower convection. The fluidic oscillator approach also decreases the friction losses in pipe networks and in nozzles/diffusers due to boundary layer disruption, so there is actually an energetic consumption savings in using this approach over steady flow. These dual advantages make the microbubble generation approach a promising component of a novel airlift loop bioreactor whose design is presented here. The equipment, control system for flow and temperature, and the optimization of the nozzle bank for the gas distribution system are presented.

Keywords
Airlift loop bioreactor; Microbubble generation; Fluidic oscillators; Transport phenomena; Biorefineries
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On the design and simulation of an airlift loop bioreactor with microbubble generation by fluidic oscillation
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Publisher
Database: Elsevier - ScienceDirect
Journal: Food and Bioproducts Processing - Volume 87, Issue 3, September 2009, Pages 215–227
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
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Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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Any Questions? feel free to contact us