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Bioseparations in Aqueous Micellar Systems Based on Excluded-Volume Interactions

Paper ID Volume ID Publish Year Pages File Format Full-Text
19618 43084 2006 8 PDF Available
Title
Bioseparations in Aqueous Micellar Systems Based on Excluded-Volume Interactions
Abstract

Protein partitioning based on micellar-induced excluded-volume interactions is studied for different aqueous nonionic micellar systems. In particular, protein partitioning in the traditional aqueous micellar two-phase system is compared with a system where a gel phase is combined with a micellar phase and with a membrane system with micelles at the feed side of the membrane. A two-phase system is created using cylindricallyshaped n-decyl tetra(ethylene oxide) (C10E4) micelles that are too large to diffuse into the gel-bead or across the membrane. Results are reported for the partition coefficient of single-component protein systems with myoglobin, ovalbumin, and BSA, and for binary protein mixtures. The individual protein partition coefficients in the mixtures follow the same protein concentration dependence as the partition coefficient obtained for the singlecomponent protein solutions.

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Bioseparations in Aqueous Micellar Systems Based on Excluded-Volume Interactions
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Publisher
Database: Elsevier - ScienceDirect
Journal: Food and Bioproducts Processing - Volume 84, Issue 1, March 2006, Pages 51-58
Authors
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us