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Simultaneous analysis of serotonin, tryptophan and tryptamine levels in common fresh fruits and vegetables in Japan using fluorescence HPLC

Paper ID Volume ID Publish Year Pages File Format Full-Text
19667 43116 2016 4 PDF Available
Title
Simultaneous analysis of serotonin, tryptophan and tryptamine levels in common fresh fruits and vegetables in Japan using fluorescence HPLC
Abstract

Serotonin is a monoamine neurotransmitter that functions as a hormone, neuromodulator, and psychoactive agent. Peripheral serotonin is involved in lipid and glucose metabolism, and it may prevent the development of metabolic syndrome. Serotonin is biosynthesized from tryptophan and can be obtained from certain foods. However, information regarding the dietary intake of serotonin is scarce. In this study, we determined the levels of serotonin and its precursors, tryptophan and tryptamine, in 38 fruits and vegetables commonly consumed in Japan using HPLC−fluorescence detection. The highest serotonin levels were found in cherry tomato (12.44±0.19 μg/g of fresh weight), and the highest tryptophan and tryptamine levels were detected in potato and kiwi (64.47±1.54 and 6.38±1.24 μg/g of fresh weight, respectively). Thus, these foods may represent excellent dietary sources of serotonin and may be used to develop effective therapeutic strategies.

Keywords
5-HW, 5-hydroxytryptophan; 5-HT, 5-hydroxytryptamine; TDC, tryptophan decarboxylaseHPLC−fluorescence detection; Serotonin; Tryptamine; Tryptophan
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Simultaneous analysis of serotonin, tryptophan and tryptamine levels in common fresh fruits and vegetables in Japan using fluorescence HPLC
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Publisher
Database: Elsevier - ScienceDirect
Journal: Food Bioscience - Volume 13, 1 March 2016, Pages 56–59
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us